Zimmer Biomet Holdings Inc. is highlighting its portfolio of orthopedic and musculoskeletal innovations this week at the American Academy of Orthopaedic Surgeons (AAOS) 2025 Annual Meeting in San Diego. During the three-day meeting, the company’s booth will feature its comprehensive hip portfolio, anchored by the new Z1 Triple-Taper Femoral Hip System, along with the latest technologies for knee and upper extremity reconstruction and key components from its robotic solutions.

In addition, Zimmer Biomet is debuting ZBX, its new Ambulatory Surgery Center (ASC) offering to surgeons and institutions looking to expand their orthopedic footprint.

“I am thrilled to showcase the collective strength and broad range of our musculoskeletal portfolio, including the introduction of several recently cleared technologies, at this year’s annual AAOS meeting,” Zimmer Biomet President/CEO Ivan Tornos said. “We are in the midst of one of the largest innovation cycles in our company’s history. Our broad hip reconstruction portfolio combined with our comprehensive knee portfolio with constructs designed to safeguard against cement and metal sensitivities, our bone-preserving stemless shoulder and now an enhanced suite of ASC solutions, squarely position us at the forefront of delivering customer-centric innovations to improve efficiency and overall patient outcomes.”

The highlights at the Zimmer Biomet booth (#3129) include:

Hip Reconstruction Technologies

• Z1 Femoral Hip System, a triple-taper design with expansive innovations within a more comprehensive system, providing more solutions to treat more patients.
• HAMMR Automated Hip Impaction System, designed to address surgeon strain, fatigue and repetitive motion associated with traditional mallet use during bone preparation and device implantation.
• OrthoGrid Hip AI, an AI-powered, fluoroscopy-based technology that provides direct anterior (DA) hip surgeons with intuitive and instantaneous intra-operative tools to assist surgeons in achieving the desired surgical outcomes for component positioning.¹
• HipInsight System, the first U.S. Food and Drug Administration (FDA)-cleared mixed reality system for hip navigation offers intuitive, intra-operative guidance that leverages the Microsoft HoloLens 2 (mixed reality headset) to help visualize and guide accurate² acetabular component placement and alignment in real-time.

Knee Reconstruction Technologies

• Persona Revision SoluTion Femur, a newly cleared revision knee implant component, part of the comprehensive Persona Revision Knee System, offering an alternative to cobalt-chrome (Co-Cr-Mo) alloy for patients with sensitivities to certain metals.
• Oxford Cementless Partial Knee, the only FDA-approved cementless partial knee implant in the United States that has been shown to be efficient^3,4 in the OR, and has been proven to have excellent longevity^5,6 worldwide.
• Persona OsseoTi Keel Tibia, a cementless anatomic tibia with a 3D printed porous tray from our clinically proven Persona Knee System^5-7 designed to deliver stable initial and biological fixation and intra-operative versatility.⁸
• Persona IQ 30 mm Stem, the world’s only smart knee implant, now in a 30 mm stem length, that collects data directly from the knee to provide post-operative recovery insights^9,10 and trends, allowing care teams to monitor and personalize the total knee arthroplasty patient experience^9-11 with the goal of improving practice efficiency.^12-15

Upper Extremities Technology

• OsseoFit Stemless Shoulder System, an anatomically shaped^16-18 asymmetric stemless shoulder implant designed for stable initial^19-22 and biological fixation^23,24 by optimizing anatomic humeral fit for stemless shoulder arthroplasty.

ASC Solutions

• ZBX, Zimmer Biomet’s new comprehensive ASC program offering surgeons an experienced partner to strategically incorporate solutions, unique to each surgeon’s needs, providing efficiency in the OR and beyond.

Zimmer Biomet is a global medical technology company with a portfolio designed to maximize mobility and improve health. Its products and suite of integrated digital and robotic technologies leverage data, data analytics, and artificial intelligence. With more than 90 years of leadership and proven expertise, Zimmer Biomet delivers quality solutions to patients and providers in more than 100 countries. The company maintains operations in over 25 countries worldwide.

References
¹ Cardenas JM, Gordon D, Waddell BS, Kitziger KJ, Peters PC Jr, Gladnick BP. Does Artificial Intelligence Outperform Humans Using Fluoroscopic-Assisted Computer Navigation for Total Hip Arthroplasty? Arthroplasty Today. 2024 May 27;27:101410. doi: 10.1016/j.artd.2024.101410. PMID: 38840694; PMCID: PMC11150909.  
² Dilbone ES, Heimann AF, Leal J, Ryan SP, Wellman SS. Evaluating the Accuracy of a Computed Tomography-Based Mixed-Reality Navigation Tool for Acetabular Component Positioning in Total Hip Arthroplasty. The Journal of Arthroplasty. 2025.
³ Pandit, H., et al. “Improved fixation in cementless unicompartmental knee replacement: five-year results of a randomized controlled trial.” JBJS 95.15 (2013): 1365-1372.
⁴ Stempin R, Kaczmarek W, Stempin K, Dutka J. Midterm Results of Cementless and Cemented Unicondylar Knee Arthroplasty with Mobile Meniscal Bearing: A Prospective Cohort Study. Open Orthop J. 2017 Oct 31;11:1173-1178. doi: 10.2174/1874325001711011173. PMID: 29290853; PMCID: PMC5721307
⁵ NJR- UK . The National Joint Registry 21st Annual Report 2024 London, 2024 [Available from: https://reports.njrcentre.org.uk/Portals/0/PDFdownloads/NJR%2021st%20Annual%20Report%202024_Knees.pdf.
⁶ AOANJRR. Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR). Hip, Knee & Shoulder Arthroplasty: 2023 Annual Report Adelaide, AOA2024 [updated 2024. Available from: https://aoanjrr.sahmri.com/documents/10180/1798900/AOANJRR+2024+Annual+Report.pdf/9d0bfe03-2282-8fc8-a424-b8d9abb82b1f?t=1727666185313.
⁷ American Joint Replacement Registry (AJRR): 2024 Annual Report. Rosemont, IL : American Academy of Orthopaedic Surgeons (AAOS), 2024. https://www.aaos.org/registries/publications/ajrr-annual-report/#:~:text=When%20citing%20any%20Annual%20Report,at%20RegistryEngagement%40aaos.org
National Joint Registry of England , Wales , Northern Ireland , the Isle of Man and Guernsey . 20th Annual Report 2023
⁸ Mueller JK, et al. Persona OsseoTi Keel Tibia Provides Stable Initial Fixation 4027.2-GLBL-en. November 2022
⁹ Cushner FD, Yergler J, ElashoffB, Aubin PM, VertaP, Scuderi GR. Staying Ahead of the Curve: The Case for Recovery Curves in Total Knee Arthroplasty. The Journal of Arthroplasty. 2024;doi:10.1016/j.arth.2024.07.039
¹⁰ Cushner FD, Sculco PK, Long WJ. The Talking Knee Is a Reality: What Your Knee Can Tell You After Total Knee Arthroplasty. J OrthopaedicExperience and Innovation. 2022;2022
¹¹ Cushner FD, Schiller P, Gross J, Mueller JK, Hunter W. A TOTAL KNEE ARTHROPLASTY PROSTHESIS CAPABLE OF REMOTE PATIENT MONITORING. OrthopaedicProceedings. 2021/06/01 2021;103-B(SUPP_9):18-18 doi:10.1302/1358-992X.2021.9.018
¹² Yocum DS, Redfern RE, Yergler JD. Delayed Recovery Following Total Knee Arthroplasty Identified by Remote Monitoring With Tibial Extension Sensors. Arthroplasty Today. 2023/10/01/ 2023;23:101188. doi: https://doi.org/10.1016/j.artd.2023.101188
¹³ Yocum D, HousholderE, Yergler J. Manipulation under Anesthesia Following TKA with Persona IQ: A Case Series. J OrthopCase Rep. Aug 2023;13(8):127-131. doi:10.13107/jocr.2023.v13.i08.3844
¹⁴ Dundon J, Aubin P, Hunter W. Objective Gait Analysis Following Total Knee Arthroplasty with a Smart Implant Directs Early Intervention with Manipulation under Anesthesia. Journal of OrthopaedicExperience & Innovation. 2024;Februarydoi:https://doi.org/10.60118/001c.89961.
¹⁵ Parikh N, Redfern R, Yocum D, Andel D V, Yergler J. MT46 Patient Experience and Outcomes with Post-Surgical Remote Monitoring for Patients with Total Knee Arthroplasty (TKA). Value in Health. 2024/06/01/ 2024;27(6, Supplement):S290. doi:https://doi.org/10.1016/j.jval.2024.03
¹⁶ Mueri, C, Snethen, K, Parisi, R, Son, Yang, Duquin, T Characterization of the Asymmetric Bone Envelope of the Proximal Humeral Metaphysis for Stemless Shoulder Implants. ORS Orthopaedic Research Society 2025 Annual Meeting, Paper No. 1175; 2025 Feb 7-11; Phoenix, Arizona .
¹⁷ Son, Y, Mueri, C, Snethen, K, Bowman, L, Parisi, R, Duquin, T Optimizing Stemless Humeral Anchors: Asymmetrical Designs for Minimizing Cortical Bone Impingement while Maximizing Cancellous Bone Purchase. ORS Orthopaedic Research Society 2025 Annual Meeting, Paper No. 2051; 2025 Feb 7-11; Phoenix, Arizona .
¹⁸ ZRR_WI_6743_24. Analysis of Potential Cortical Perforation for the OsseoFit Stemless Shoulder. Zimmer Biomet Internal Research Report on File.
¹⁹ Snethen, K, Mueri, C, Kriska, T, Son, Y, Bandi, M The Sensitivity of the Stability of Stemless Humeral Implants to Surgical, Patient and Design Factors in Reverse Shoulder Arthroplasty. Presented at the ORS Orthopaedic Research Society Annual Meeting; 2023, Dallas, Texas .
²⁰ Snethen, K, Son, Y, Mueri, C, Bischoff, J The Effect of Press-fit on Initial Stability in Stemless Shoulder Arthroplasty. Presented at the ISTA International Society for Technology in Arthroplasty Annual Meeting; 2022, Maui, Hawaii .
²¹ Snethen, K, Mueri, C, Son, Y, Parisi, R, Duquin, T The Effect of Geometric Design on Initial Stability of Stemless Shoulder Implants. ORS Orthopaedic Research Society 2025 Annual Meeting, Paper No. 1168; 2025 Feb 7-11; Phoenix, Arizona .
²² ZBTR_30118. Anchor-Level Micromotion of the OsseoFit Stemless Shoulder with Application in Anatomic Total Shoulder Arthroplasty. Zimmer Biomet Internal Design Verification Report on File.
²³ Gupta, G Evaluation of Bony Ingrowth Implant Materials in an In Vivo Sheep Long Bone Defect Model 12-04/12-07, February 2013. 32.
²⁴ Gupta, G OsseoTi Porous Metal For Enhanced Bone Integration: an Animal Study. White Paper. 2014. Form No. BMET0718.0-GBL • REV1214.

Laboratory and animal studies are not necessarily indicative of clinical performance.

Persona IQ: The objective kinematic data generated by the Canary Canturio Tibial Extension with CHIRP System are not intended to support clinical decision-making and have not been shown to provide any clinical benefit.