The orthopedic device landscape is undergoing changes fueled by an increase in mergers and acquisitions. Specialized players are being absorbed by industry leaders, driven by a desire for new technologies, expanded markets, and enhanced capabilities.

To navigate this year, we’ve launched this essential guide to every major orthopedic design and technology M&A deal. Stay ahead of the curve, track key partnerships, and understand the industry’s reshaping with concise updates and insightful analysis. Return to this page to track the changes in the orthopedic device industry throughout 2025.

Acumed—TECHFIT Digital Surgery

This asset acquisition gives Acumed full ownership of TECHFIT’s proprietary technologies. This includes its proprietary digital surgical planning and reconstruction technology, enabling patient-specific implants and preoperative planning for complex craniofacial procedures.
Date of Announcement: November 5, 2025
Value: Not disclosed
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WRS Group—Avanos Medical

Avanos is selling its Game Ready orthopedic rental business to WRS Group. Game Ready is used in the pain management and rehabilitation of patients recovering from orthopedic surgery or sports-related injuries.
Date of Announcement: October 23, 2025
Value: Not disclosed
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Boston Scientific—Nalu Medical

Boston Scientific has been a strategic investor in Nalu since 2017. The Nalu neurostimulation system provides targeted relief for adults living with severe, intractable pain originating in peripheral nerves using peripheral nerve stimulation (PNS).
Date of Announcement: October 17, 2025
Value: ~$533 million
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Keensight Capital—Isto Biologics

TSCP will retain a minority stake, alongside Isto Biologics’ management team. Keensight will leverage its experience and expertise to further grow Isto into a global leader in biomaterials for tissue regeneration. Through its extensive international network and with the support of the Keensight Performance team, Keensight will contribute to accelerating Isto’s growth strategy, both organically and through acquisitions.
Date of Announcement: September 17, 2025
Value: Not disclosed
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Highridge Medical—Accelus

Highridge has acquired Accelus FlareHawk and Toro expandable interbody fusion systems, as well as the LineSider pedicle screw system. The company now has more advanced offerings for both the hospital and ambulatory surgery center (ASC) settings.
Date of Announcement: September 2, 2025
Value: Not disclosed
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Driving Force—Wenzel Spine

Driving Force acquired Wenzel Spine’s Vertebral Motion Analysis (VMA) technology, which uses dynamic fluoroscopy and proprietary software to generate objective, quantifiable, accurate, consistent, and reliable (med-legal) evidence of spinal instability injuries often missed by standard MRI and X-ray.
Date of Announcement: August 27, 2025
Value: Not disclosed
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Tenon Medical—SiVantage

Tenon acquired SI joint specific assets from SiVantage. The acquisition includes SiVantage’s SImmetry and SImmetry+ technologies, adding multiple approaches to variable sacro pelvic anatomy to its SI portfolio.
Date of Announcement: August 1, 2025
Value: Not disclosed
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Channel-Markers Medical—Avanos Medical

Avanos divested its Hyaluronic Acid (HA) product line to Channel-Markers Medical. The divested portfolio includes TriVisc and GenVisc 850 products, which are used to treat osteoarthritis (OA) pain in the knee.
Date of Announcement: July 31, 2025
Value: Not disclosed
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ARCHIMED—ZimVie

ARCHIMED, an investment firm focused on healthcare industries, will acquire the global life sciences leader in the dental implant market that develops, manufactures, and delivers a comprehensive portfolio of products and solutions designed to support dental tooth replacement and restoration procedures.
Date of Announcement: July 21, 2025
Value: $19 per share—enterprise value $730 million
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Zimmer Biomet—Monogram Technologies

Monogram’s semi- and fully autonomous robotic technologies will add new, differentiated capabilities to expand Zimmer Biomet’s ROSA robotics platform and suite of navigation and enabling technologies.
Date of Announcement: July 14, 2025 (closed October 7)
Value: $4.04 per share—enterprise value $168 million, equity value $177 million
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SK Capital Partners—Lisi Medical

Lisi Medical is a Neyron, France-based medtech contract development and manufacturing organization (CDMO) that produces high-precision metal components and assemblies for medical device original equipment manufacturers (OEMs).
Date of Announcement: July 9, 2025 (closed November 3)
Value: Not disclosed
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Companion Spine—Paradigm Spine

Wurmlingen, Germany-based Paradigm Spine designs, develops, markets, and distributes a range of spine implants to treat spine pain-related disorders. Coflex and CoFix—available in the U.S.—have been on the market for 12 years in the U.S. and 20 years outside the U.S.
Date of Announcement: July 8, 2025
Value: Not disclosed
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Highridge Medical—Avista Healthcare Partners

Highridge sold EBI, its Bone Healing business, to the healthcare investor. This transaction allows the company to focus exclusively on spine technology
Date of Announcement: June 4, 2025
Value: Not disclosed
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moveUP.care—Deep Structure.ai

moveUP is a digital orthopedics company that specializes in personalized rehabilitation and remote patient monitoring. Deep Structure is a digital health company focused on artificial intelligence (AI)-driven orthopedic surgery planning and rehabilitation.
Date of Announcement: March 10, 2025
Value: Not disclosed
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Forécreu—Grover Precision

Transaction expands Forécreu’s cannulated bar technology offerings for orthopedic device manufacturers.
Date of Announcement: March 4, 2025
Value: Not disclosed
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Dementra Holding—GetSet Surgical

Demetra Holding has acquired a 51% stake in GetSet Surgical, a leading Swiss-based spine surgical solutions provider. This will broaden Demetra Holdings’ place in the spine sector and enhance its infection management solutions and orthopedic offerings.
Date of Announcement: February 27, 2025
Value: Not disclosed
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ARCH Medical Solutions—KISS Technologies

ARCH has acquired KISS Technologies, expanding its medical device capabilities and reinforcing its commitment to innovation, quality, and superior patient care. With this transition, KISS Technologies will join the ARCH – American Prosthetic Components business.
Date of Announcement: February 24, 2025
Value: Not disclosed
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Medtronic—Nanovis

Medtronic acquired certain nano surface technology assets and rights to Nanovis’ OsteoSync titanium pads. Medtronic plans to use them to develop its next-generation PEEK interbody fusion devices.
Date of Announcement: February 12, 2025
Value: Not disclosed
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Globus Medical—Nevro Corp.

Globus Medical entered an agreement to acquire Nervo Corp. Globus Medical will acquire all shares of Nevro for $5.85 per share, in cash. The deal is expected to close late in the second quarter of 2025.
Date of Announcement: February 6, 2025 (closed April 3, 2025)
Value: $250 million
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Stryker—Viscogliosi Brothers

Stryker began a deal to sell its U.S. spinal implants business to investment firm Viscogliosi Brothers. A newly formed company will be created, called VB Spine. The agreement also includes a binding offer to acquire Stryker’s spinal implants business in France.
Date of Announcement: January 28, 2025 (closed April 1, 2025)
Value: Not disclosed
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Zimmer Biomet—Paragon 28

Englewood, Colo.-based Paragon 28 was established in 2010. The company touts a suite of surgical offerings and product systems spanning all major foot and ankle segments.
Date of Announcement: January 28, 2025 (closed April 21, 2025)
Value: $30 per share ($1.1 billion equity value, $1.2 billion enterprise value)
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Aspen Medical Products—Advanced Orthopaedics

Aspen Medical Products has acquired Advanced Orthopaedics, a leading manufacturer and supplier of bracing solutions and orthopedic soft goods. This strategic purchase Aspen’s enhances Aspen’s global reach and expands its portfolio into the bracing and support market.
Date of Announcement: January 13, 2025
Value: Not disclosed
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Tyber Medical—Intech—Resolve Surgical Technologies

Private equity firm Montagu is acquiring Tyber Medical, a medical device company providing private label development and manufacturing services to medtech OEMs. Subject to customary regulatory approvals and closing conditions, Tyber Medical will be combined with Montagu’s existing investments in Resolve and Intech.
Date of Announcement: January 13, 2025 (closed April 24, 2025)
Value: Not disclosed
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Stryker—Inari Medical

Stryker has acquired all issued and outstanding common shares of Inari Medical. This will complement Stryker’s Neurovascular business as well as enter the high-growth peripheral vascular segment.
Date of Announcement: January 6, 2025
Value: $80 per share (about $4.9 billion)
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Fusion Orthopedics—Metalogix

Metalogix expands Fusion Ortho’s solutions with Circular Static Frames, Dynamic Frames, Delta Frames, and a soon-to-be-released, novel Mini-Rail System.
Date of Announcement: January 3, 2025
Value: Not disclosed
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Check out 2024’s M&A roundup.